Renal Hemophilic Pseudotumors

Review Article

Renal Hemophilic Pseudotumors


Emel Gürkan

Affiliation: Department of Haematology, C¸ ukurova University Medical School, Adana, Turkey

Submission date: 1st July 2009, Revision date: 2nd August 2009, Acceptance date: 10th August 2009


ABSTRACT

Severe hemophilic patients are prone to develop long‐term sequelae such as pseudotumor formation caused by repeated and unresolved hematomas leading to subsequent encapsulated mass lesion. Among these, renal hemophilic pseudotumors are seen as a rather rare event. Once developed, this serious condition should be approached carefully, first by maintaining adequate hemostasis with appropriate factor replacement therapy and, later on, complete surgical excision should be targeted. Without surgical intervention, complete resolution is generally not possible. Other treatment modalities such as radiotherapy may be helpful in addition to surgery preoperatively in order to reduce bleeding complications. However, experience of this approach is limited to those pseudotumors of other sites such as bone and pelvic pseudotumors. Rarely, a true pseudotumor may mimic a malignancy; therefore, accurate assessment by radiological means is required. Considering the difficulties in management, it is of great importance to constitute early substitutive treatment for the prevention of pseudotumors.

Keywords: renal pseudotumor, hemophilia, management
Correspondence: Emel Gürkan, Çukurova University Faculty of Medicine, Department of Hematology, 01330 Adana, Turkey